Pfizer, Inc.



  • Project Overview
  • Project Details

Carolina, Puerto Rico

August 2003

85,000 sq. ft. 

Construction Management

Torcon was the Construction Manager for a series of expansion and upgrade projects at Pfizer‘s (Wyeth) plant in Carolina, Puerto Rico. Through this work, Pfizer now has one of the largest lyophilization installations in the world.

Among the projects completed is a three-story, 85,000 sq. ft. Piperacillin Master Plan Project, a new manufacturing facility flanked by existing manufacturing buildings. This new building houses two formulation areas encompassing 26,000 sq. ft., as well as clean room production areas from Class 100 to Class 100,000.

Additionally, Torcon infilled a two-story courtyard area in the center of a parenteral production facility to provide space for sample storage, two new aseptic/Class 100 AHU’s and new formulation and weigh rooms.

Torcon also completed a series of utility upgrades and relocations, including a central utility plant with two 100-ton process glycol chillers, a 5,000 lb. per hour clean steam generator, a 2,000 kva substation and replacement of two 2,000 gpm fire pumps. A tank farm was also added to feed the entire site. The new plant includes a 400,000 gallon process water tank, a 20,000 gallon potable water tank, and a 4,100 gallon below-ground cistern to distribute, chlorinate and monitor all water systems at the site.

Torcon’s initial work at the site was the Piperacillin Phase II project, which required the expansion of a manufacturing facility that produces penicillin-type products. This work added a 5,000 sq. ft., two-story building housing a Class 100 filling suite, vial washing and an expansion of a GMP material center. Torcon also completed a two phase expansion to an existing Class 100 production area, which added four 450 sq. ft. Lyophilizers.